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Non-systemic transmission of tick-borne diseases: a network approach

机译:蜱传疾病的非系统性传播:网络方法

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摘要

Tick-Borne diseases can be transmitted via non-systemic (NS) transmission.This occurs when tick gets the infection by co-feeding with infected ticks onthe same host resulting in a direct pathogen transmission between the vectors,without infecting the host. This transmission is peculiar, as it does notrequire any systemic infection of the host. The NS transmission is the mainefficient transmission for the persistence of the Tick-Borne Encephalitis virusin nature. By describing the heterogeneous ticks aggregation on hosts through a\hyphenation{dynamical} bipartite graphs representation, we are able tomathematically define the NS transmission and to depict the epidemiologicalconditions for the pathogen persistence. Despite the fact that the underlyingnetwork is largely fragmented, analytical and computational results show thatthe larger is the variability of the aggregation, and the easier is for thepathogen to persist in the population.
机译:Tick-Borne疾病可以通过非系统(NS)传播方式传播。这种情况发生在当tick虫通过与同一宿主上受感染的tick虫共同喂食而感染时,导致病原体在载体之间直接传播而不感染宿主。这种传播是特殊的,因为它不需要宿主的任何全身感染。 NS传播是维持Tick-Borne脑炎病毒本质上持久性的最有效途径。通过通过\连字符{动态}二部图表示来描述主机上的异类s虫聚集,我们能够在数学上定义NS传播并描述病原体持久性的流行病学条件。尽管基础网络很大程度上是分散的,但分析和计算结果表明,聚集的可变性越大,病原体在种群中的保留越容易。

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